Comparison of Two phototherapy Methods for Reducing Bilirubin of Neonates: Continuous vs. intermittent

Mohammad Mehdi Houshmandi Rakhshaneh Goodarzi, Fatemeh Yousefi, Behnaz Khamesan, Yaghoob Hamedi, Darioush Fakhrai


 60% of neonates and 80% of preterm infants may have jaundice and 10.5% of them usually require phototherapy. Given that the phototherapy can cause the separation of mother and infant, difficulties in breastfeeding and concerns about damage to genetic material, any way to minimize the amount of received radiation would have positive results. The purpose of this study was to compare the effect of continuous and intermittent phototherapy to minimize levels of neonatal bilirubin levels. This study was a randomized clinical trial, conducted among 100 infants at Children's Hospital of Bandar-Abbas. Infants randomly divided into two groups: 39 infants were in intermittent phototherapy (a hour phototherapy and a clock interrupt phototherapy) and 45 infants in continuous phototherapy (two hours and forty-five minutes, phototherapy and 15 minutes off phototherapy). Demographic data, type of feeding and phototherapy complications for neonatal were recorded. Total bilirubin was measured 12 hours after starting phototherapy then with 12 hours interval. The mean age, weight, nutrition and gender distribution was not significantly different between the two groups. Bilirubin levels were significantly decreased in both groups (p<0.001). Decrease of Hyperbilirubinemia in continuous group was more than alternative group (p<0. 01).there was no Significant difference between the duration of phototherapy and complication rates in both groups . Continuous phototherapy was more effective than intermittent to decrease levels of hyperbilirubinemia in full term neonates, but duration of phototherapy for comparing two methods were identical.

Keyword: jaundice, indirect bilirubin, phototherapy, intermittent, continuous phototherapy

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